Rates the confidence in network meta-analysis results
CINeMA is a web application that simplifies the evaluation of confidence in the findings fron network meta-analysis. CINeMA is broadly based on the GRADE framework, with several conceptual and semantic differences [5]. It covers 6 domains: (i) within-study bias (referring to the impact of risk of bias in the included studies), (ii) reporting bias (referring to publication and other reporting bias), (iii) indirectness, (iv) imprecision, (v) heterogeneity, and (vi) incoherence. Users upload their data, produce network plots and define the analysis and effect measure. The dataset should include assessments of study-level risk of bias (RoB) and judgments on indirectness. CINeMA calls the netmeta routine in R to estimate relative effects and heterogeneity. Users are then guided through a systematic evaluation of the six domains