Assesses whether a meta-analysis has enough information
TSA is a user-friendly software application which makes it easy for authors of systematic reviews and meta-analysis to apply a number of advanced sequential hypothesis testing techniques to their meta-analyses. It helps in quantifying the statistical reliability of data in the cumulative meta-analysis adjusting significance levels for sparse data and repetitive testing on accumulating data. In TSA the addition of each trial in a cumulative meta-analysis is regarded as an interim meta-analysis and TSA controls the risks for type I and type II errors and helps to clarify whether additional trials are needed. Additionally, TSA provides us with important information regarding the required sample size for such trials.
